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moderated NATAP/IDWeek: Doravirine-Rational Design Review

Jules Levin
 


www.natap.org
                                    IN THIS NEW POZ List ALL pictures/tables are shown only at the very bottom of email report….

Rational Design of Doravirine (DOR): A Review of Development From Bench to Patients

 Merck has ongoing clinical study of 2-ART drug regimen combining doravirine with only long-acting MK8591 their new nuke-type of ART but different, and could also be a long-acting PrEP.

It has been recruiting & is ongoing: Not Yet Recruiting New: MK-8591 With Doravirine and Lamivudine in Participants Infected With Human Immunodeficiency Virus Type 1 (MK-8591-011)


reported at IDWeek:

 IDWeek: Switch to Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (DOR/3TC/TDF) Maintains Virologic Suppression Through 48 Weeks: Results of the DRIVE-SHIFT Trial - (10/06/18)


Reported by Jules Levin

IDWeek; San Francisco, CA; October 3–7, 2018

 

Carey Hwang, MD, PhD; Ming-Tain Lai, PhD; Daria Hazuda, PhD

Merck & Co., Inc., Kenilworth, NJ, USA

poster pdf
































Reprinted with permission from Feng M, et al. Antimicrob Agents Chemother. 2015;59(1):590-598 



























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