can one today set up a gpib connection on a win 10 system and talk to thisDepends on what you mean by "talk to".
If you mean just communicate with the scope, yes off course if you have a
working GPIB setup.
If you mean the adjustment software, no. It is a DOS application which won't
run on Win10 and also it requires an old ISA card NI GPIBII/IIA.
I don't think the adjustment would fix your problem anyway.