FYI, the link to the software and sound files is located here.
Also, I use Windows 10 Pro 32 bit on my laptop and have 100% success with both installation and using the QSI programmer. I have seen a LOT of different comments on both sides but all I did was follow the instructions and it worked. I have used it on machines with XP Pro, Windows 7 Pro, and Windows 10 Pro.
One other option is JMRI DecoderPro. This FREE software works to ONLY program decoders, including QSI. It works with almost any OS and it has a huge membership to help with all of it's different functions. The ONLY software capable of CHANGING sound files in a QSI decoder requires both their software and programmer. But if all you want to do is to change CVs , addresses, speed curves, volume, lights, functions, etc. DecoderPro will work fine.