System is Win11, DXKeeper 16.3.2, WSJT 2.5, JtAlert 2.5, Windows Runtime 5.0.12
Been working correctly for two days. First, uninstalled McFee; Found out that there was an uninstall for McFee by doing a search to get rid of the rest of the stuff. That helped, but not completely. For some reason, can not find a newer mouse driver (2006) then what came with 11 late last 2021. So, running the mouse driver in Win 8 mode. Same as WSJT and JTAlert.
Finally, went backwards and installed JTAlert 2.16.17, running in Win 8 mode. BINGO! It's back working as should be! I had read that JTAlert 2,5, which I really liked, needed a newer version of Windows Runtime and just could not find anything newer then the 5.0.12, available in HamApps. If you find a newer version, please let me know.